Immunoinformatics Study on Early 4 Protein of Human Papillomavirus Type 16 for Cervical Cancer Vaccine Peptide Candidate
نویسندگان
چکیده
منابع مشابه
Construction a DNA Vaccine Containing Human Papillomavirus Type 16 Early Genes as a Potential Vaccine for Cervical Cancer Prevention and Therapy
Background and Objectives: Some of the human papillomaviruses (HPVs) can infect genital tracts and are sometimes associated with anogenital tract cancers. HPVs induced cervical cancers through the expression of E6 and E7 genes by inactivating the tumor suppressor proteins. In this study, E6 and E7 genes were chosen in order to construct an expression vector which is able to express ...
متن کاملconstruction a dna vaccine containing human papillomavirus type 16 early genes as a potential vaccine for cervical cancer prevention and therapy
background and objectives: some of the human papillomaviruses (hpvs) can infect genital tracts and are sometimes associated with anogenital tract cancers. hpvs induced cervical cancers through the expression of e6 and e7 genes by inactivating the tumor suppressor proteins. in this study, e6 and e7 genes were chosen in order to construct an expression vector which is able to express target prote...
متن کاملHuman papillomavirus type 16 variants and risk of cervical cancer.
There are substantial data demonstrating that human papillomaviruses (HPVs) are the sexually transmitted etiologic agents of cervical cancer (1). HPV type 16 (HPV16) is the most common HPV type detected in tumors, accounting for 50% of cancers and their precursors, called high-grade squamous intraepithelial lesions (HSILs) (2). Preliminary studies (3–16) have suggested that variants of HPV16 ma...
متن کاملIntegration of human papillomavirus type 16 in cervical cancer cells
Cervical cancer remains an important cause of women morbidity and mortality. The progression of cervical pathology correlates with the HPV integration into the host genome. However, the data on the viral integration status in cervical dysplasias are controversial. The aim of the current study was to evaluate the status of HPV integration in two types of cervical pathology - invasive and non inv...
متن کاملCervical cancer and the human papillomavirus vaccine.
Background As a former sufferer from cervical cancer, I obviously gave a huge whoop of joy at the recent announcement about the human papillomavirus (HPV) vaccine. At last a simple, effective weapon to use against the disease. What’s not to like? But to be frank, I was sure I’d be a lone voice, at least in the wilderness of the lay domain. In an age when the fpa’s (Family Planning Association) ...
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ژورنال
عنوان ژورنال: Jurnal Biodjati
سال: 2019
ISSN: 2548-1606,2541-4208
DOI: 10.15575/biodjati.v4i2.5414